# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4324283 | ADME | Clearance in human liver microsomes measured per mg of protein | Homo sapiens | 7 | ALA4321846 | microsome format | Scientific Literature | |
2. | ALA4324284 | Binding | Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate preincubated for 20 mins followed by substrate addition in presence of ATP at Km concentration after 20 mins by rapidfire mass spectrometry analysis | Homo sapiens | 8 | ALA4321846 | single protein format | Scientific Literature | |
3. | ALA4324285 | Binding | Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate preincubated for 20 mins followed by substrate addition in presence of 1 mM ATP after 10 mins by rapidfire mass spectrometry analysis | Homo sapiens | 8 | ALA4321846 | single protein format | Scientific Literature | |
4. | ALA4324286 | Binding | Inhibition of ERK1/2 in human A375 cells assessed as inhibition of ERK phosphorylation after 2 hrs | Homo sapiens | 11 | ALA4321846 | cell-based format | Scientific Literature | |
5. | ALA4324287 | Binding | Inhibition of ERK1/2 in human A375 cells assessed as inhibition of RSK phosphorylation after 2 hrs | Homo sapiens | 11 | ALA4321846 | cell-based format | Scientific Literature | |
6. | ALA4324288 | Physicochemical | 1-Octanol-PBS buffer distribution coefficient, log D of compound at pH 7.4 | 8 | ALA4321846 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4324289 | Physicochemical | Solubility of compound in PBS at pH 7.4 after 24 hrs | 8 | ALA4321846 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4324294 | ADME | Intrinsic clearance in rat hepatocytes measured per million of cells | Rattus norvegicus | 5 | ALA4321846 | cell-based format | Scientific Literature | |
9. | ALA4324295 | ADME | Intrinsic clearance in human hepatocytes measured per million of cells | Homo sapiens | 5 | ALA4321846 | cell-based format | Scientific Literature | |
10. | ALA4324296 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 5 | ALA4321846 | cell-based format | Scientific Literature | |
11. | ALA4324297 | Binding | Inhibition of human ERG | Homo sapiens | 5 | ALA4321846 | single protein format | Scientific Literature |