| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4373201 | B | Inhibition of Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a using Suc-LY-AMC as substrate preincubated for 10 mins followed by substrate addition and measured over 1 hr by fluorescence assay | Escherichia coli | 106 | single protein format | Scientific Literature | ||
| 2. | ALA4373202 | B | Inhibition of Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a at 200 uM using Suc-LY-AMC as substrate preincubated for 10 mins followed by substrate addition and measured over 1 hr by fluorescence assay relative to control | Escherichia coli | 106 | single protein format | Scientific Literature | ||
| 3. | ALA4373203 | F | Growth inhibition of wild-type Escherichia coli BW25113 at 100 uM measured at 1 hr time interval for 15 to 24 hrs | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4373204 | F | Growth inhibition of wild-type Escherichia coli BW25113 at 100 uM under nitric oxide stress condition measured at 1 hr time interval for 15 to 24 hrs in presence of DPTA NONOate | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4373205 | F | Growth inhibition of ClpP-deficient Escherichia coli JW0427-1 at 100 uM measured at 1 hr time interval for 15 to 24 hrs | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4373206 | F | Growth inhibition of ClpP-deficient Escherichia coli JW0427-1 at 100 uM under nitric oxide stress condition measured at 1 hr time interval for 15 to 24 hrs in presence of DPTA NONOate | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4373207 | A | Cytotoxicity against human HeLa cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 8. | ALA4373208 | A | Cytotoxicity against human HepG2 cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 9. | ALA4373209 | A | Cytotoxicity against human A549 cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 10. | ALA4373211 | A | Inhibition of bovine alpha-chymotrypsin assessed as residual activity at 200 uM relative to control | Bos taurus | 14 | single protein format | Scientific Literature | ||
| 11. | ALA4373214 | B | Reversible binding affinity to Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a up to 320 uM measured after cessation of compound treatment by SPR analysis | Escherichia coli | 4 | single protein format | Scientific Literature |
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