#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4338388	Binding	Activation of STING in human PBMC assessed as induction of INFalpha secretion at 12.5 uM incubated for 16 hrs by ProcartaPlex assay relative to 2'3'cGAMP	Homo sapiens	38	ALA4334523	single protein format	Scientific Literature
2.	ALA4338395	Binding	Binding affinity to recombinant human wild-type STING assessed as change in melting temperature at 150 uM by SYPRO orange dye based differential scanning fluorimetric method	Homo sapiens	39	ALA4334523	single protein format	Scientific Literature
3.	ALA4338396	Binding	Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase reporter gene assay	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
4.	ALA4338397	Binding	Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
5.	ALA4338398	Binding	Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
6.	ALA4338399	Binding	Activation of recombinant human STING haplotype R232H mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
7.	ALA4338400	Binding	Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
8.	ALA4338401	Binding	Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
9.	ALA4338402	Functional	Cytotoxicity against human PBMC-derived monocytes assessed as CD3-negative CD14 positive monocyte viability at 12.5 uM incubated for 16 hrs by Zombie-NIR staining-based flow cytometry relative to control	Homo sapiens	38	ALA4334523	cell-based format	Scientific Literature
10.	ALA4338403	Binding	Activation of STING in human PBMC assessed as induction of INFgamma secretion at 12.5 uM incubated for 16 hrs by ProcartaPlex assay relative to 2'3'cGAMP	Homo sapiens	38	ALA4334523	single protein format	Scientific Literature
11.	ALA4338404	Binding	Activation of STING in human PBMC assessed as induction of TNFalpha secretion at 12.5 uM incubated for 16 hrs by ProcartaPlex assay relative to 2'3'cGAMP	Homo sapiens	38	ALA4334523	single protein format	Scientific Literature
12.	ALA4338406	Binding	Ratio of EC50 for recombinant human wild-type STING expressed in 293T cells in absence of digitonin A to EC50 for recombinant human wild-type STING expressed in 293T cells in presence of digitonin A	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
13.	ALA4338407	Binding	Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay relative to 2'3'cGAMP	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
14.	ALA4338408	Binding	Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay relative to 2'3'cGAMP	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
15.	ALA4338409	Binding	Activation of recombinant human STING haplotype R232H mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay relative to 2'3'cGAMP	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
16.	ALA4338410	Binding	Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay relative to 2'3'cGAMP	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
17.	ALA4338411	Binding	Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase reporter gene assay relative to 2'3'cGAMP	Homo sapiens	39	ALA4334523	cell-based format	Scientific Literature
18.	ALA4338412	ADME	Cytotoxicity against human PBMC-derived CD3-positive T cells assessed as effect on cell viability at 12.5 uM incubated for 16 hrs by Zombie-NIR staining-based flow cytometry	Homo sapiens	38	ALA4334523	cell-based format	Scientific Literature
19.	ALA4719626	Functional	Induction of type I IFN production in mouse RAW-Lucia ISG-KO-STING cells at 0.08 to 60 ug/ml incubated for 48 hrs by luciferase reporter gene assay	Mus musculus	12	ALA4715794	tissue-based format	Scientific Literature
20.	ALA4719630	ADME	Stability in presence of nuclease P1 assessed as half life at 7 ug incubated for 2 hrs by HPLC analysis	Penicillium citrinum	3	ALA4715794	single protein format	Scientific Literature