# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4349850 | Functional | Antiproliferative activity against human Ramos cells assessed as reduction in cell viability after 24 hrs by resazurin dye-based spectrophotometric method | Homo sapiens | 6 | ALA4346731 | cell-based format | Scientific Literature | |
2. | ALA4349851 | Functional | Antiproliferative activity against human Ramos cells assessed as reduction in cell viability after 72 hrs by resazurin dye-based spectrophotometric method | Homo sapiens | 6 | ALA4346731 | cell-based format | Scientific Literature | |
3. | ALA4349852 | Functional | Antiproliferative activity against human Jurkat J16 cells assessed as reduction in cell viability after 24 hrs by resazurin dye-based spectrophotometric method | Homo sapiens | 6 | ALA4346731 | cell-based format | Scientific Literature | |
4. | ALA4349853 | Functional | Antiproliferative activity against human Jurkat J16 cells assessed as reduction in cell viability after 72 hrs by resazurin dye-based spectrophotometric method | Homo sapiens | 6 | ALA4346731 | cell-based format | Scientific Literature | |
5. | ALA4349856 | Functional | Induction of apoptosis in human Ramos cells assessed as caspase-3 activation at 1 uM using AcDEVD-AMC as substrate preincubated for up to 8 hrs followed by substrate addition and measured after 60 mins by spectrophotometric method | Homo sapiens | 3 | ALA4346731 | cell-based format | Scientific Literature | |
6. | ALA4349857 | Functional | Induction of apoptosis in human Ramos cells assessed as caspase-3 activation at 3 uM using AcDEVD-AMC as substrate preincubated for up to 8 hrs followed by substrate addition and measured after 60 mins by spectrophotometric method | Homo sapiens | 3 | ALA4346731 | cell-based format | Scientific Literature | |
7. | ALA4349860 | Functional | Induction of apoptosis in human Jurkat J16 cells assessed as caspase-3 activation at 1 uM using AcDEVD-AMC as substrate preincubated for up to 8 hrs followed by substrate addition and measured after 60 mins by spectrophotometric method | Homo sapiens | 3 | ALA4346731 | cell-based format | Scientific Literature | |
8. | ALA4349861 | Functional | Induction of apoptosis in human Jurkat J16 cells assessed as caspase-3 activation at 3 uM using AcDEVD-AMC as substrate preincubated for up to 8 hrs followed by substrate addition and measured after 60 mins by spectrophotometric method | Homo sapiens | 3 | ALA4346731 | cell-based format | Scientific Literature | |
9. | ALA4349864 | Functional | Induction of apoptosis in human Ramos cells assessed as increase in cleaved PARP1 protein expression at 1 uM after 2 to 8 hrs by immunoblotting analysis | Homo sapiens | 3 | ALA4346731 | cell-based format | Scientific Literature | |
10. | ALA4349867 | Functional | Induction of apoptosis in human Ramos cells assessed as increase in cleaved PARP1 protein expression at 1 uM after 2 to 8 hrs in presence of caspace-inhibitor Q-VD-Oph by immunoblotting analysis | Homo sapiens | 3 | ALA4346731 | cell-based format | Scientific Literature | |
11. | ALA4349869 | Binding | Inhibition of SK1 (unknown origin) at 10 uM using sphingosine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by fluorescence based assay relative to control | Homo sapiens | 3 | ALA4346731 | single protein format | Scientific Literature | |
12. | ALA4349870 | Binding | Inhibition of SK2 (unknown origin) at 10 using sphingosine as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay relative to control | Homo sapiens | 3 | ALA4346731 | single protein format | Scientific Literature |