# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4432093 | ADME | Intrinsic clearance in mouse liver microsomes at 1 uM preincubated for 10 mins followed by NADPH addition measured up to 30 mins by LC-MS/MS analysis | Mus musculus | 39 | ALA4431325 | microsome format | Scientific Literature | |
2. | ALA4432094 | Functional | Antiviral activity against Hepatitis B virus infected in human HepDE19 cells assessed as reduction in viral DNA level after 5 days by dot blot assay | Hepatitis B virus | 58 | ALA4431325 | organism-based format | Scientific Literature | |
3. | ALA4432095 | ADME | Cytotoxicity against human HepDE19 cells assessed as reduction in cell viability after 5 days by CCK8 assay | Homo sapiens | 58 | ALA4431325 | cell-based format | Scientific Literature | |
4. | ALA4432096 | Toxicity | Selectivity index, ratio of CC50 for human HepDE19 cells to EC50 for Hepatitis B virus infected in human HepDE19 cells | 39 | ALA4431325 | cell-based format | Scientific Literature | ||
5. | ALA4432099 | Physicochemical | Aqueous solubility in 50 mM phosphate buffer at pH 6.5 after overnight incubation by HPLC based lyophilized solubility assay | 58 | ALA4431325 | small-molecule physicochemical format | Scientific Literature |