| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4407229 | B | Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androstene-3,17-dione at 0.1 uM measured after 1 hr relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA4407230 | B | Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androstene-3,17-dione at 0.5 uM measured after 1 hr relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4407231 | B | Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androstene-3,17-dione at 1 uM measured after 1 hr relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 4. | ALA4407232 | B | Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androstene-3,17-dione measured after 1 hr | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4407233 | A | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as effect on cell proliferation at 0.1 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA4407234 | A | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as effect on cell proliferation at 0.5 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA4407235 | A | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as effect on cell proliferation at 1 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay (Rvb = 100%) | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 8. | ALA4407237 | A | Stability of the compound in human liver S9 fraction at 10 uM measured after 1 hr by NADPH by HPLC-MS analysis | Homo sapiens | 6 | subcellular format | Scientific Literature |
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