# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4478794 | B | Allosteric inhibition of HCV genotype 1b NS5A infected in human l389lucubi- neo/NS3-375.1-containing Huh7ET cells assessed as RNA replication/translation after 4 days by luciferase reporter gene assay | Hepatitis C virus subtype 1b | 20 | ALA4477222 | assay format | Scientific Literature | |
2. | ALA4478796 | A | Cytotoxicity against human Huh7ET cells assessed as reduction in cell viability after 4 days | Homo sapiens | 20 | ALA4477222 | cell-based format | Scientific Literature | |
3. | ALA4478797 | B | Allosteric inhibition of HCV genotype 1a NS5A infected in human W11.8 cells assessed as reduction in viral RNA replication after 4 days by ELISA | Hepatitis C virus subtype 1a | 20 | ALA4477222 | cell-based format | Scientific Literature | |
4. | ALA4478798 | A | Cytotoxicity against human W11.8 cells assessed as reduction in cell viability after 4 days | Homo sapiens | 20 | ALA4477222 | cell-based format | Scientific Literature | |
5. | ALA5261234 | F | Antiviral activity against Hepatitis C virus subtype 1b infected in Huh-7 cells transfected with HCV subgenomic replicon for NS5B polymerase assessed as inhibition of viral replication measured upto 96 hrs by luciferase reporter gene assay | Hepacivirus hominis | 10 | ALA5260802 | organism-based format | Scientific Literature | |
6. | ALA5261235 | F | Antiviral activity against Hepatitis C virus subtype 1b infected in Huh-7 cells transfected with HCV subgenomic replicon for NS5B polymerase assessed as inhibition of viral replication measured upto 96 hrs in presence of 40% of human serum by luciferase reporter gene assay | Hepacivirus hominis | 10 | ALA5260802 | organism-based format | Scientific Literature | |
7. | ALA5261236 | T | Cytotoxicity against human Huh-7 cells transfected with HCV subgenomic replicon for NS5B polymerase assessed as reduction in cell viability | Homo sapiens | 10 | ALA5260802 | cell-based format | Scientific Literature |