# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4335428 | ADME | Cytotoxicity against C57BL/6J mouse Bone marrow macrophage cells assessed as reduction in cell viability at < 10 uM after 48 hrs by CCK-8 assay | Mus musculus | 11 | ALA4334440 | cell-based format | Scientific Literature | |
2. | ALA4335433 | Functional | Inhibition of RANKL/M-CSF-induced osteoclastogenesis in C57BL/6J mouse Bone marrow macrophage cells assessed as decrease in number of osteoclasts at 0.1 to 1 uM compound for every 2 days and measured after 7 days by TRAP staining based light microscopic method | Mus musculus | 1 | ALA4334440 | cell-based format | Scientific Literature | |
3. | ALA4335434 | Functional | Inhibition of RANKL/M-CSF-induced osteoclastogenesis in C57BL/6J mouse Bone marrow macrophage cells assessed as decrease in area of osteoclasts at 0.1 to 1 uM compound for every 2 days and measured after 7 days by TRAP staining based light microscopic method | Mus musculus | 1 | ALA4334440 | cell-based format | Scientific Literature |