# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4381855 | B | Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
2. | ALA4381856 | B | Antagonist activity at mouse alpha1beta1epsilondelta nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Mus musculus | 14 | cell-based format | Scientific Literature | ||
3. | ALA4381857 | B | Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
4. | ALA4381858 | B | Antagonist activity at rat alpha6alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
5. | ALA4381859 | B | Antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
6. | ALA4381860 | B | Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
7. | ALA4381861 | B | Antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
8. | ALA4381866 | B | Antagonist activity at rat alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
9. | ALA4381867 | B | Selectivity ratio of IC50 for antagonist activity at mouse alpha1beta1epsilondelta nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes | 14 | cell-based format | Scientific Literature | |||
10. | ALA4381868 | B | Selectivity ratio of IC50 for antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
11. | ALA4381869 | B | Selectivity ratio of IC50 for antagonist activity at rat alpha6alpha3beta4 nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
12. | ALA4381870 | B | Selectivity ratio of IC50 for antagonist activity at rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
13. | ALA4381871 | B | Selectivity ratio of IC50 for antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
14. | ALA4381872 | B | Selectivity ratio of IC50 for antagonist activity at rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes to IC50 for antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes | Rattus norvegicus | 14 | cell-based format | Scientific Literature |