#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4427348	Binding	Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assay	Homo sapiens	25	ALA4425164	single protein format	Scientific Literature
2.	ALA4427349	Binding	Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ and 4% HSA by glucose 6-phosphate dehydrogenase coupled assay	Homo sapiens	25	ALA4425164	single protein format	Scientific Literature
3.	ALA4427350	Binding	Activation of human recombinant glucokinase assessed as enzyme affinity for glucose using 5 mM glucose as substrate in presence of NAD+ by by glucose 6-phosphate dehydrogenase coupled assay	Homo sapiens	25	ALA4425164	single protein format	Scientific Literature
4.	ALA4427351	Binding	Activation of human recombinant glucokinase assessed as Vmax ratio using 0.16 to 80 mM of glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assay relative to control	Homo sapiens	25	ALA4425164	single protein format	Scientific Literature
5.	ALA4427352	Physicochemical	Solubility of the compound in PBS at pH 7.4		6	ALA4425164	small-molecule physicochemical format	Scientific Literature
6.	ALA4427353	ADME	Fraction unbound in rat plasma	Rattus norvegicus	2	ALA4425164	cell-free format	Scientific Literature
7.	ALA4427354	ADME	Fraction unbound in mouse plasma	Mus musculus	2	ALA4425164	cell-free format	Scientific Literature
8.	ALA4427355	ADME	Fraction unbound in human plasma	Homo sapiens	2	ALA4425164	cell-free format	Scientific Literature
9.	ALA4427360	Functional	Antidiabetic activity in po dosed Sprague-Dawley rat assessed as decrease in blood glucose AUC measured at 0.5 to 5 hrs by OGTT	Rattus norvegicus	1	ALA4425164	organism-based format	Scientific Literature
10.	ALA4427361	Functional	Antidiabetic activity in Sprague-Dawley rat assessed as decrease in blood glucose AUC at 100 mg/kg, po measured at 0.5 to 5 hrs by OGTT	Rattus norvegicus	1	ALA4425164	organism-based format	Scientific Literature
11.	ALA4427362	ADME	Clearance in rat at 0.5 mg/kg, iv	Rattus norvegicus	7	ALA4425164	organism-based format	Scientific Literature
12.	ALA4427363	ADME	Clearance in mouse at 1 mg/kg, iv	Mus musculus	2	ALA4425164	organism-based format	Scientific Literature
13.	ALA4427364	ADME	Volume of distribution at steady state in rat at 0.5 mg/kg, iv	Rattus norvegicus	3	ALA4425164	organism-based format	Scientific Literature
14.	ALA4427365	ADME	Volume of distribution at steady state in mouse at 1 mg/kg, iv	Mus musculus	2	ALA4425164	organism-based format	Scientific Literature
15.	ALA4427366	ADME	Half life in rat at 0.5 mg/kg, iv	Rattus norvegicus	3	ALA4425164	organism-based format	Scientific Literature
16.	ALA4427367	ADME	Half life in mouse at 1 mg/kg, iv	Mus musculus	2	ALA4425164	organism-based format	Scientific Literature
17.	ALA4427368	ADME	Oral bioavailability in rat at 2 mg/kg	Rattus norvegicus	3	ALA4425164	organism-based format	Scientific Literature
18.	ALA4427369	ADME	Oral bioavailability in mouse at 5 mg/kg	Mus musculus	2	ALA4425164	organism-based format	Scientific Literature
19.	ALA4427370	ADME	AUC in rat at 2 mg/kg, po	Rattus norvegicus	3	ALA4425164	organism-based format	Scientific Literature
20.	ALA4427371	ADME	AUC in mouse at 5 mg/kg, po	Mus musculus	2	ALA4425164	organism-based format	Scientific Literature