# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4395365 | Functional | Antitrypanosomal activity against bloodstream form of Trypanosoma brucei gambiense Feo reduction in parasite growth after 72 hrs by resazurin dye based fluorescence assay | Trypanosoma brucei gambiense | 93 | ALA4393692 | organism-based format | Scientific Literature | |
2. | ALA4395366 | ADME | Cytotoxicity against human AB943 cells assessed as reduction in cell viability after 5 days resazurin dye based fluorescence assay | Homo sapiens | 26 | ALA4393692 | cell-based format | Scientific Literature | |
3. | ALA4395367 | Toxicity | Selectivity index, ratio of IC50 for human AB943 cells to IC50 of bloodstream form of Trypanosoma brucei gambiense Feo | 26 | ALA4393692 | assay format | Scientific Literature | ||
4. | ALA4672554 | Functional | Antitrypanosomal activity against bloodstream form of Trypanosoma brucei gambiense Feo assessed as reduction in parasite growth | Trypanosoma brucei gambiense | 21 | ALA4665886 | organism-based format | Scientific Literature | |
5. | ALA4672555 | Functional | Antileishmanial activity against Leishmania major FV1 assessed as reduction in parasite growth | Leishmania major | 31 | ALA4665886 | organism-based format | Scientific Literature | |
6. | ALA4672556 | ADME | Cytotoxicity against human BJ cells after 24 hrs by redox-sensitive dye based fluorescent assay | Homo sapiens | 31 | ALA4665886 | cell-based format | Scientific Literature | |
7. | ALA4672557 | ADME | Cytotoxicity against human MRC5 cells after 24 hrs by redox-sensitive dye based fluorescent assay | Homo sapiens | 31 | ALA4665886 | cell-based format | Scientific Literature | |
8. | ALA4672558 | Toxicity | Therapeutic index, ratio of average IC50 for human MRC5 and BJ cells to IC50 for antileishmanial activity against Leishmania major | 31 | ALA4665886 | assay format | Scientific Literature |