#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4311709	Binding	Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl-alpha -D-glucopyranoside by microbeta counting method	Homo sapiens	22	ALA4308914	cell-based format	Scientific Literature
2.	ALA4311710	Binding	Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-alpha -D-glucopyranoside by microbeta counting method	Homo sapiens	22	ALA4308914	cell-based format	Scientific Literature
3.	ALA4311711	ADME	Permeability of the compound at pH 7.4 by PAMPA assay		13	ALA4308914	assay format	Scientific Literature
4.	ALA4311712	ADME	Total clearance in Sprague-Dawley rat at 0.4 mg/kg, iv	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
5.	ALA4311713	ADME	Volume of distribution at steady sate in Sprague-Dawley rat at 0.4 mg/kg, iv	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
6.	ALA4311714	ADME	Half life in Sprague-Dawley rat at 0.4 mg/kg, iv	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
7.	ALA4311715	ADME	Cmax in Sprague-Dawley rat at 30 mg/kg, po	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
8.	ALA4311716	ADME	Tmax in Sprague-Dawley rat at 30 mg/kg, po	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
9.	ALA4311717	ADME	Oral bioavailability in Sprague-Dawley rat at 30 mg/kg	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
10.	ALA4311719	ADME	Drug excretion in bile duct cannulated Sprague-Dawley rat urine at 0.3 mg/kg, iv administered as single dose after 24 hrs by LCMS analysis	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
11.	ALA4311721	ADME	Drug excretion in bile duct cannulated Sprague-Dawley rat bile at 0.3 mg/kg, iv administered as single dose after 24 hrs by LCMS analysis	Rattus norvegicus	2	ALA4308914	organism-based format	Scientific Literature
12.	ALA4311722	Functional	Antidiabetic activity in Sprague-Dawley rat assessed as reduction in blood glucose AUC (0 to 2 hrs) at 0.3 mg/kg, po dosed just prior to sucrose loading measured up to 120 mins by sucrose tolerance test relative to control	Rattus norvegicus	1	ALA4308914	organism-based format	Scientific Literature
13.	ALA4311723	Functional	Antidiabetic activity in Sprague-Dawley rat assessed as reduction in blood glucose AUC (0 to 2 hrs) at 1 mg/kg, po dosed just prior to sucrose loading measured up to 120 mins by sucrose tolerance test relative to control	Rattus norvegicus	1	ALA4308914	organism-based format	Scientific Literature
14.	ALA4311724	Functional	Antidiabetic activity in Sprague-Dawley rat assessed as reduction in blood glucose AUC (0 to 2 hrs) at 3 mg/kg, po dosed just prior to sucrose loading measured up to 120 mins by sucrose tolerance test relative to control	Rattus norvegicus	1	ALA4308914	organism-based format	Scientific Literature
15.	ALA4311725	ADME	Drug uptake in Sprague-Dawley rat kidney at 0.3 mg/kg, iv administered as single dose after 2 hrs by LCMS analysis	Rattus norvegicus	3	ALA4308914	organism-based format	Scientific Literature
16.	ALA4311726	ADME	Drug uptake in Sprague-Dawley rat kidney at 0.3 mg/kg, iv administered as single dose after 24 hrs by LCMS analysis	Rattus norvegicus	3	ALA4308914	organism-based format	Scientific Literature
17.	ALA4311727	ADME	Drug uptake in Sprague-Dawley rat kidney at 0.3 mg/kg, iv administered as single dose after 72 hrs by LCMS analysis	Rattus norvegicus	3	ALA4308914	organism-based format	Scientific Literature
18.	ALA4311728	ADME	Drug uptake in Sprague-Dawley rat kidney assessed as unchanged drug level at 0.3 mg/kg, iv administered as single dose after 72 hrs by LCMS analysis relative to control	Rattus norvegicus	3	ALA4308914	organism-based format	Scientific Literature
19.	ALA4311729	Functional	Antidiabetic activity in Sprague-Dawley rat assessed as reduction in blood glucose AUC (0 to 2 hrs) at 0.3 to 3 mg/kg, po dosed just prior to sucrose loading measured up to 120 mins by sucrose tolerance test relative to control	Rattus norvegicus	1	ALA4308914	organism-based format	Scientific Literature
20.	ALA4311730	Toxicity	Gastrointestinal toxicity in Sprague-Dawley rat assessed as induction of diarrhea at 0.3 to 3 mg/kg, po dosed just prior to sucrose loading measured up to 120 mins during sucrose tolerance test relative to control	Rattus norvegicus	1	ALA4308914	organism-based format	Scientific Literature