# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4314447 | Functional | Antiviral activity against HCV genotype 1a infected in human Huh7.5 cells assessed as reduction in viral replication by measuring HCV core antigen level by ELISA | Hepacivirus hominis | 39 | ALA4311989 | organism-based format | Scientific Literature | |
2. | ALA4314448 | Binding | Inhibition of recombinant HCV genotype 1a NS5B polymerase coincubated with HCV international ribosome entry site template sequence containing nucleotide residues 21-371 of HCV 5'-untranslated Escherichia coli DNA polymerase I region incubated for 3 hrs by scintillation/luminescence counter method | Hepatitis C virus subtype 1a | 39 | ALA4311989 | single protein format | Scientific Literature | |
3. | ALA4314453 | Binding | Potency index, ratio of VCH-759 IC50 to compound IC50 for HCV genotype 1a recombinant NS5B polymerase coincubated with HCV international ribosome entry site template sequence containing nucleotide residues 21-371 of HCV 5'-untranslated Escherichia coli DNA polymerase I region | Hepatitis C virus subtype 1a | 6 | ALA4311989 | single protein format | Scientific Literature |