| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4349816 | B | Inhibition of PDE3A (unknown origin) | Homo sapiens | 2 | ALA4346730 | single protein format | Scientific Literature | |
| 2. | ALA4349817 | B | Inhibition of bovine corpus striatum PDE10A using [3H]cAMP or [3H]cGMP as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by liquid scintillation counting method | Bos taurus | 15 | ALA4346730 | assay format | Scientific Literature | |
| 3. | ALA4349818 | P | Solubility in artificial interstitial fluid at pH 5 by HPLC analysis | 12 | ALA4346730 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4349819 | B | Inhibition of human ERG at 1 uM relative to control | Homo sapiens | 12 | ALA4346730 | single protein format | Scientific Literature | |
| 5. | ALA4349820 | B | Inhibition of human N-terminal FLAG-tagged PDE10A (1 to 90 residues) expressed in using African green monkey COS7 cells using [3H]cAMP or [3H]cGMP as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4346730 | cell-based format | Scientific Literature | |
| 6. | ALA4349821 | P | Chromatographic hydrophobicity index, log D of the compound at pH 7.4 by reverse-phase HPLC analysis | 8 | ALA4346730 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4349822 | B | Inhibition of PDE1 (unknown origin) | Homo sapiens | 1 | ALA4346730 | assay format | Scientific Literature | |
| 8. | ALA4349823 | B | Inhibition of PDE2A (unknown origin) | Homo sapiens | 1 | ALA4346730 | single protein format | Scientific Literature | |
| 9. | ALA4349824 | B | Inhibition of PDE4 (unknown origin) | Homo sapiens | 1 | ALA4346730 | protein format | Scientific Literature | |
| 10. | ALA4349825 | B | Inhibition of PDE5A (unknown origin) | Homo sapiens | 1 | ALA4346730 | single protein format | Scientific Literature | |
| 11. | ALA4349826 | B | Inhibition of PDE6 (unknown origin) | Homo sapiens | 1 | ALA4346730 | protein format | Scientific Literature | |
| 12. | ALA4349827 | B | Inhibition of PDE7B (unknown origin) | Homo sapiens | 1 | ALA4346730 | single protein format | Scientific Literature | |
| 13. | ALA4349828 | B | Inhibition of PDE8A (unknown origin) | Homo sapiens | 1 | ALA4346730 | single protein format | Scientific Literature | |
| 14. | ALA4349829 | B | Inhibition of PDE9A (unknown origin) | Homo sapiens | 1 | ALA4346730 | single protein format | Scientific Literature | |
| 15. | ALA4349830 | B | Inhibition of PDE11A (unknown origin) | Homo sapiens | 1 | ALA4346730 | single protein format | Scientific Literature | |
| 16. | ALA4349831 | A | Oral bioavailability in Wistar rat at 3 mg/kg | Rattus norvegicus | 2 | ALA4346730 | organism-based format | Scientific Literature | |
| 17. | ALA4349832 | A | Unbound brain-to-plasma concentration ratio in Wistar rat at 3 mg/kg, po | Rattus norvegicus | 2 | ALA4346730 | organism-based format | Scientific Literature | |
| 18. | ALA4349833 | A | Half life in Wistar rat at 0.3 mg/kg, iv | Rattus norvegicus | 2 | ALA4346730 | organism-based format | Scientific Literature | |
| 19. | ALA4349834 | A | Volume of distribution at steady state in Wistar rat at 0.3 mg/kg, iv | Rattus norvegicus | 1 | ALA4346730 | organism-based format | Scientific Literature | |
| 20. | ALA4349835 | A | Total clearance in Wistar rat at at 0.3 mg/kg, iv | Rattus norvegicus | 1 | ALA4346730 | organism-based format | Scientific Literature |
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