| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4337362 | F | Antimicrobial activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of bacterial growth under Mueller-Hinton conditions without iron supplementation | Pseudomonas aeruginosa | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA4337363 | F | Antimicrobial activity against siderophore-producing Pseudomonas aeruginosa PAO1 assessed as inhibition of bacterial growth at 0.125 to 128 ug/mL under iron-supplemented succinate minimal medium in the presence of 50 uM of FeCl3 | Pseudomonas aeruginosa | 4 | organism-based format | Scientific Literature | ||
| 3. | ALA4337365 | F | Induction of fluorescent pyoverdine-1 siderophore production in siderophore-producing Pseudomonas aeruginosa PAO1 at 0.125 to 128 ug/mL incubated for 24 hrs under iron-supplemented succinate minimal medium in the presence of 50 uM of FeCl3 | Pseudomonas aeruginosa | 4 | organism-based format | Scientific Literature | ||
| 4. | ALA4337366 | B | Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assay | Pseudomonas aeruginosa | 7 | single protein format | Scientific Literature | ||
| 5. | ALA4337368 | B | Potency index, ratio of IC50 for Me-alpha-D-mannoside to IC50 for test compound for inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assay | Pseudomonas aeruginosa | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4337369 | F | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation incubated for 24 to 25 hrs at 50 uM by WST8 dye based Diggle-protocol method relative to control | Pseudomonas aeruginosa | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA4337370 | F | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation incubated for 24 to 25 hrs at 20 uM by WST8 dye based Diggle-protocol method relative to control | Pseudomonas aeruginosa | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4337372 | F | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation incubated for 24 to 25 hrs at 20 uM in presence of sub-inhibitory concentration of tobramycin by WST8 dye based Diggle-protocol method relative to control | Pseudomonas aeruginosa | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4337373 | A | Toxicity in Pseudomonas aeruginosa PAO1 incubated for 24 to 25 hrs at 20 uM in presence of sub-inhibitory concentration of tobramycin by WST8 dye based Diggle-protocol method relative to control | Pseudomonas aeruginosa | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4337375 | F | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation incubated for 8 hrs at 20 uM by crystal violet based O'Toole method relative to control | Pseudomonas aeruginosa | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA4337376 | T | Toxicity in human CFBEdeltaF cells isolated from CF patient at 20 uM incubated for 24 hrs by LDH assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA5033559 | B | Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 13. | ALA5033560 | B | Inhibition of full-length DC-SIGN (unknown origin) expressed in human monocyte derived dendritic cells assessed as inhibition of binding to recombinant HCMV gB using flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA5033561 | F | Antiviral activity against HCMV infected in U-937 cells expressed in DC-SIGN using flow cytometry | Human betaherpesvirus 5 | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA5033562 | F | Potency index, ratio of Mannan IC50 to test compound IC50 for antiviral activity against HCMV infected in U-937 cells expressed in DC-SIGN using flow cytometry | Human betaherpesvirus 5 | 4 | organism-based format | Scientific Literature | ||
| 16. | ALA5033563 | B | Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 hrs by luciferase assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA5033564 | B | Relative inhibitory potency, ratio of alpha-D-mannoside IC50 to test compound IC50 for inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 hrs by luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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