# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4396764 | Binding | Inhibition of human recombinant JAK1 assessed as phosphorylation of substrate at 10 uM using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins in the presence of ATP by LANCE assay relative to control | Homo sapiens | 26 | ALA4393739 | single protein format | Scientific Literature | |
2. | ALA4396765 | Binding | Inhibition of human recombinant JAK2 assessed as phosphorylation of substrate at 10 uM using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins in the presence of ATP by LANCE assay relative to control | Homo sapiens | 26 | ALA4393739 | single protein format | Scientific Literature | |
3. | ALA4396767 | Functional | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as inhibition of NO generation pre-incubated for 2 hrs followed by LPS stimulation and measured after 18 hrs by Griess method | Mus musculus | 26 | ALA4393739 | cell-based format | Scientific Literature |