| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4339346 | F | Antiinflammatory activity in human HepG2 cells xenografted Balb/c nude mouse assessed as reduction in TNFalpha protein expression at 1 mg/kg, ip administered every 2 days for 20 days and measured every 2 days by immunohistochemistry | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA4339347 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 3. | ALA4339348 | F | Cytotoxicity against human QGY7703 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 4. | ALA4339349 | F | Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 5. | ALA4339350 | A | Cytotoxicity against human HHL5 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 6. | ALA4339351 | A | Cytotoxicity against human LO2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 7. | ALA4339352 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 6.0 uM incubated for 24 hrs by MTT assay | Mus musculus | 58 | cell-based format | Scientific Literature | ||
| 8. | ALA4339353 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNF-alpha production at 6.0 uM preincubated for 2 hrs followed by LPS stimulaton measured after 22 hrs by ELISA relative to control | Mus musculus | 50 | cell-based format | Scientific Literature | ||
| 9. | ALA4339354 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated IL-6 production 6.0 uM preincubated for 2 hrs followed by LPS stimulaton measured after 22 hrs by ELISA relative to control | Mus musculus | 50 | cell-based format | Scientific Literature | ||
| 10. | ALA4339355 | F | Induction of apoptosis in human SMMC7721 cells assessed as increase in apoptotic cell population at 4.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4339356 | F | Induction of apoptosis in human HepG2 cells assessed as increase in apoptotic cell population at 4.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4339357 | F | Induction of apoptosis in human QGY7703 cells assessed as increase in apoptotic cell population at 4.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4339358 | F | Induction of apoptosis in human QGY7703 cells assessed as increase in apoptotic cell population at 2.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4339359 | F | Induction of apoptosis in human HepG2 cells assessed as increase in apoptotic cell population at 2.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4339360 | F | Induction of apoptosis in human SMMC7721 cells assessed as increase in apoptotic cell population at 2.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4339361 | F | Induction of apoptosis in human QGY7703 cells assessed as increase in apoptotic cell population at 4.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4339362 | F | Induction of apoptosis in human HepG2 cells assessed as increase in apoptotic cell population at 4.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4339363 | F | Induction of apoptosis in human SMMC7721 cells assessed as increase in apoptotic cell population at 4.0 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4339364 | F | Induction of apoptosis in human HepG2 cells assessed as increase in Bax expression up to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4339365 | F | Induction of apoptosis in human HepG2 cells assessed as reduction in Bcl-2 expression up to 4 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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