| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4357304 | B | Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated for 12 hrs by fluorescence polarization assay | Homo sapiens | 13 | ALA4354833 | single protein format | Scientific Literature | |
| 2. | ALA4357325 | B | Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferation | Mus musculus | 3 | ALA4354833 | cell-based format | Scientific Literature | |
| 3. | ALA4357326 | B | Inhibition of STAT5b phosphorylation in mouse BaF3/FLT3-ITD cells at 25 uM after 6 hrs by Western blot analysis relative to control | Mus musculus | 1 | ALA4354833 | cell-based format | Scientific Literature | |
| 4. | ALA4357328 | F | Antitumor activity against mouse BaF3/FLT3-ITD cells implanted in NSG mouse assessed as induction of tumor growth regression at 200 mg/kg, sc QD for 14 days relative to control | Mus musculus | 1 | ALA4354833 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!