| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4382964 | B | Protac activity at cereblon/cullin 4A/BET in human RS4:11 cells assessed as reduction in c-myc protein levels at 10 pM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4382966 | F | Growth inhibition of human RS4:11 cells after 96 hrs by CCK8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4382967 | F | Growth inhibition of human MV4-11 cells after 96 hrs by CCK8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 4. | ALA4382968 | F | Growth inhibition of human MOLM13 cells after 96 hrs by CCK8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 5. | ALA4382969 | B | Binding affinity to human BRD4 BD1 (44 to 168 residues) by fluorescence polarization assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 6. | ALA4382970 | B | Binding affinity to human BRD2 BD1 (72 to 205 residues) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4382971 | B | Binding affinity to human BRD2 BD2 (349 to 460 residues) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4382972 | B | Binding affinity to human BRD3 BD1 (24 to 144 residues) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4382973 | B | Binding affinity to human BRD3 BD2 (306 to 417 residues) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4382974 | B | Binding affinity to human BRD4 BD2 (333 to 460 residues) by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4382983 | F | Induction of apoptosis in human RS4:11 cells assessed as PARP cleavage at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4383001 | B | Protac activity at cereblon/cullin-4A/BET in human MV4-11 cells assessed as reduction in c-myc protein levels at 30 pM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4383060 | B | Protac activity at cereblon/cullin 4A/BRD2 in human RS4:11 cells assessed as BRD2 degradation at 1 to 10 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4383061 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells assessed as BRD3 degradation at 1 to 10 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4383062 | B | Protac activity at cereblon/cullin 4A/BRD4 in human RS4:11 cells assessed as BRD4 degradation at 1 to 10 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4383063 | B | Protac activity at cereblon/cullin 4A/BRD2 in human MV4-11 cells assessed as BRD2 degradation at 1 to 10 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4383064 | B | Protac activity at cereblon/cullin 4A/BRD3 in human MV4-11 cells assessed as BRD3 degradation at 1 to 10 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4383065 | B | Protac activity at cereblon/cullin 4A/BRD4 in human MV4-11 cells assessed as BRD4 degradation at 1 to 10 uM after 3 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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