# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417242 | B | Inhibition of Wnt/beta-Catenin signaling (unknown origin) expressed in recombinant human Wnt-3a-induced Wnt-HEK293 cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 26 | ALA4414663 | cell-based format | Scientific Literature | |
2. | ALA4417245 | F | Growth inhibition of human SW480 cells at 50 uM by Cell-titer-fluor reagent based assay relative to control | Homo sapiens | 9 | ALA4414663 | cell-based format | Scientific Literature | |
3. | ALA4417246 | F | Growth inhibition of human SW480 cells by Cell-titer-fluor reagent based assay | Homo sapiens | 11 | ALA4414663 | cell-based format | Scientific Literature | |
4. | ALA4417247 | B | Inhibition of Wnt/beta-Catenin signaling (unknown origin) expressed in recombinant human Wnt-3a-induced Wnt-HEK293 cells assessed as increase in beta-catenin degradation at 1 uM by Western blot analysis | Homo sapiens | 3 | ALA4414663 | cell-based format | Scientific Literature | |
5. | ALA4417248 | F | Induction of Axin-1 protein expression in recombinant human Wnt-3a-induced Wnt-HEK293 cells at 1 uM by Western blot analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
6. | ALA4417249 | F | Induction of Axin-1 protein expression in recombinant human Wnt-3a-induced Wnt-HEK293 cells at 1 uM by fluorescence microscopy | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
7. | ALA4417251 | B | Activation of AMPK in HEK293 cells with Axin-1 knockdown assessed as increase in AMPK phosphorylation at T172 residue at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
8. | ALA4417252 | B | Inhibition of Wnt/beta-Catenin signaling in human SW480 cells incubated for 24 hrs by TCF/LEF dual-luciferase reporter assay | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
9. | ALA4417253 | B | Inhibition of Wnt/beta-Catenin signaling in human SW620 cells incubated for 24 hrs by TCF/LEF dual-luciferase reporter assay | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
10. | ALA4417254 | F | Induction of Axin-1 protein expression in human SW620 cells by Western blot analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
11. | ALA4417255 | B | Inhibition of Wnt/beta-Catenin signaling in human SW620 cells assessed as reduction in beta-catenin protein level at 1 to 30 uM by Western blot analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
12. | ALA4417256 | B | Inhibition of Wnt/beta-Catenin signaling in human SW620 cells assessed as reduction in c-Myc mRNA expression at 10 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
13. | ALA4417257 | B | Inhibition of Wnt/beta-Catenin signaling in human SW620 cells assessed as reduction in cyclinD1 mRNA expression at 10 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
14. | ALA4417258 | B | Inhibition of Wnt/beta-Catenin signaling in human SW620 cells assessed as reduction in MMP7 mRNA expression at 10 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
15. | ALA4417259 | B | Inhibition of Wnt/beta-Catenin signaling in human SW620 cells assessed as reduction in S100A4 mRNA expression at 10 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
16. | ALA4417260 | B | Activation of AMPK in human SW620 cells assessed as increase in AMPK phosphorylation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
17. | ALA4417261 | B | Activation of AMPK in human SW620 cells assessed as increase in ACC phosphorylation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
18. | ALA4417262 | F | Inhibition of colony formation in human SW620 cells incubated for 14 days by crystal violet staining based assay | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
19. | ALA4417263 | F | Inhibition of colony formation in human SW480 cells incubated for 14 days by crystal violet staining based assay | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature | |
20. | ALA4417264 | F | Inhibition of colony formation in human HT-29 cells incubated for 14 days by crystal violet staining based assay | Homo sapiens | 1 | ALA4414663 | cell-based format | Scientific Literature |