# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4352897 | A | Cytotoxicity against human HepG2.2.15 cells assessed as cell viability measured after 72 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
2. | ALA4352898 | B | Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level supplemented with fresh medium containing compound every 2 days and measured after 6 days by RT-PCR analysis relative to control | Hepatitis B virus | 28 | cell-based format | Scientific Literature | ||
3. | ALA4352899 | B | Inhibition of capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM supplemented with fresh medium containing compound every 2 days and measured after 6 days by RT-PCR analysis | Hepatitis B virus | 7 | cell-based format | Scientific Literature | ||
4. | ALA4352900 | T | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for capsid protein in Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction in viral DNA level | 7 | cell-based format | Scientific Literature | |||
5. | ALA4352901 | B | Inhibition of capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15 cells assessed as reduction in viral DNA level at 4 uM measured after 72 hrs by PCR analysis relative to control | Hepatitis B virus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4352902 | B | Inhibition of capsid protein in wild type Hepatitis B virus infected in human HepG2.2.15 cells assessed as reduction of viral DNA level at 4 uM measured after 72 hrs by PCR analysis relative to control | Hepatitis B virus | 2 | cell-based format | Scientific Literature | ||
7. | ALA4352907 | B | Inhibition of capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15 cells assessed as reduction in viral DNA level measured after 72 hrs by PCR analysis | Hepatitis B virus | 3 | cell-based format | Scientific Literature | ||
8. | ALA4352908 | T | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for capsid protein in lamivudine/entecavir-resistant Hepatitis B virus harboring rtL180M/rtM204V/rt184L mutant infected in human HepG2.2.15 cells assessed as reduction in viral DNA level | 3 | cell-based format | Scientific Literature | |||
9. | ALA5158574 | T | Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as reduction in cell growth by CCK8 assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
10. | ALA5158576 | T | Cytotoxicity against human HepG2 2.2.15 cells infected with Hepatitis B virus assessed as inhibition of cell growth at 0.4 uM incubated for 6 days by RT PCR analysis relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
11. | ALA5158577 | F | Antiviral activity against Hepatitis B virus infected in human HepG2 2.2.15 cells assessed as inhibition of DNA replication | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
12. | ALA5158578 | T | Selectivity index, ratio of CC50 for human HepG2.2.2.15 cells to IC50 for Hepatitis B virus infected in human HepG2.2.2.15 cells | 8 | cell-based format | Scientific Literature |