# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4480750 | Binding | Antiribosomal activity against wild type bacterial ribosomes assessed as inhibition of luciferase production by cell-free translation assay | Bacteria | 2 | ALA4480383 | subcellular format | Scientific Literature | |
2. | ALA4480751 | ADME | Antiribosomal activity against humanized bacterial ribosome incorporating complete decoding A site from human mitochondrial ribosome Mit13 assessed as inhibition of luciferase production by cell-free translation assay | Homo sapiens | 2 | ALA4480383 | assay format | Scientific Literature | |
3. | ALA4480752 | ADME | Antiribosomal activity against humanized bacterial ribosome incorporating A1555G mutant of human mitochondrial ribosome assessed as inhibition of luciferase production by cell-free translation assay | Homo sapiens | 2 | ALA4480383 | assay format | Scientific Literature | |
4. | ALA4480753 | ADME | Antiribosomal activity against humanized bacterial ribosome incorporating human cytoplasmic ribosome Cyt14 assessed as inhibition of luciferase production by cell-free translation assay | Homo sapiens | 2 | ALA4480383 | assay format | Scientific Literature | |
5. | ALA4480754 | Binding | Selectivity ratio of IC50 for antiribosomal activity against humanized bacterial ribosome incorporating complete decoding A site from human mitochondrial ribosome Mit13 to IC50 for antiribosomal activity against wild type bacterial ribosomes | 2 | ALA4480383 | assay format | Scientific Literature | ||
6. | ALA4480755 | Binding | Selectivity ratio of IC50 for antiribosomal activity against humanized bacterial ribosome incorporating A1555G mutant of human mitochondrial ribosome to IC50 for antiribosomal activity against wild type bacterial ribosomes | 2 | ALA4480383 | assay format | Scientific Literature | ||
7. | ALA4480756 | Binding | Selectivity ratio of IC50 for antiribosomal activity against humanized bacterial ribosome incorporating human cytoplasmic ribosome Cyt14 to IC50 for antiribosomal activity against wild type bacterial ribosomes | 2 | ALA4480383 | assay format | Scientific Literature | ||
8. | ALA4480757 | Functional | Antibacterial activity against Escherichia coli AG001 | Escherichia coli | 2 | ALA4480383 | organism-based format | Scientific Literature | |
9. | ALA4480758 | Functional | Antibacterial activity against Klebsiella pneumoniae AG215 | Klebsiella pneumoniae | 2 | ALA4480383 | organism-based format | Scientific Literature | |
10. | ALA4480759 | Functional | Antibacterial activity against Enterobacter cloacae AG290 | Enterobacter cloacae | 2 | ALA4480383 | organism-based format | Scientific Literature | |
11. | ALA4480760 | Functional | Antibacterial activity against Acinetobacter baumannii AG309 | Acinetobacter baumannii | 2 | ALA4480383 | organism-based format | Scientific Literature | |
12. | ALA4480761 | Functional | Antibacterial activity against Pseudomonas aeruginosa AG220 | Pseudomonas aeruginosa | 2 | ALA4480383 | organism-based format | Scientific Literature | |
13. | ALA4480762 | Functional | Antibacterial activity against Methicillin-resistant Staphylococcus aureus AG038 | Staphylococcus aureus | 2 | ALA4480383 | organism-based format | Scientific Literature |