| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4400024 | A | Half life in human microsomes at 1 uM in presence of NADPH | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 2. | ALA4400025 | A | Half life in rat microsomes at 1 uM in presence of NADPH | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 3. | ALA4400026 | P | Solubility of compound in pH 7.4 PBS at 100 ug/ml incubated for 2 hrs by LC-MS/MS analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA4400028 | B | Selectivity ratio of Ki for IP6K3 (unknown origin) to Ki for IP6K1 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4400029 | B | Selectivity ratio of Ki for IP6K2 (unknown origin) to Ki for IP6K1 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4400030 | B | Inhibition of IP6K3 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4400031 | B | Inhibition of IP6K2 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4400032 | B | Inhibition of IP6K1 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4400033 | B | Inhibition of IP6K3 (unknown origin) incubated for 120 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4400034 | B | Inhibition of IP6K2 (unknown origin) incubated for 30 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4400035 | B | Binding affinity to IP6K1 (unknown origin) assessed as change in melting temperature by SYPRO orange dye-based assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 12. | ALA4400036 | B | Binding affinity to IP6K1 (unknown origin) assessed as change in melting temperature at 1.11 uM by SYPRO orange dye based assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 13. | ALA4400037 | B | Inhibition of IP6K1 (unknown origin) incubated for 30 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assay | Homo sapiens | 29 | single protein format | Scientific Literature | ||
| 14. | ALA4400038 | B | Inhibition of human recombinant ABL (27 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4400039 | B | Inhibition of human recombinant ALK (1058 to end residues) assessed as residual activity at 10 uM using KKKSPGEYVNIEF as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4400040 | B | Inhibition of human full length recombinant AMPKalpha1 assessed as residual activity at 10 uM using AMARAASAAALAR as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4400041 | B | Inhibition of recombinant human ASK1 (649 to 946 residues) assessed as residual activity at 10 uM using myelin basic protein as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4400042 | B | Inhibition of recombinant full-length human AURKA I31F mutant assessed as residual activity at 10 uM using LRRASLG as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4400043 | B | Inhibition of human full length recombinant CAMKI assessed as residual activity at 10 uM using KKLRRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4400044 | B | Inhibition of human full length recombinant CDK1/cyclinB assessed as residual activity at 10 uM using Histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]ATP at Km concentration by radiometric assay relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature |
The page will load shortly, Thanks for your patience!