# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4384935 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 10 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
2. | ALA4384936 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 10 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
3. | ALA4384951 | F | Reduction in hypoxia-induced TLR4 mRNA expression in Sprague-Dawley rat cardiomyocytes at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by RT-qPCR analysis relative to untreated control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA4384952 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced IL-1beta mRNA expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by RT-qPCR analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature |