# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4373344 | Functional | Positive allosteric modulation of Gqi5-fused human M4 AChR assessed as increase in acetylcholine-induced calcium mobilization | Homo sapiens | 32 | ALA4371085 | single protein format | Scientific Literature | |
2. | ALA4373345 | Functional | Positive allosteric modulation of Gqi5-fused human M4 AChR assessed as increase in acetylcholine-induced calcium mobilization relative to acetylcholine alone | Homo sapiens | 32 | ALA4371085 | single protein format | Scientific Literature | |
3. | ALA4373346 | ADME | Fraction unbound in rat plasma | Rattus norvegicus | 18 | ALA4371085 | cell-free format | Scientific Literature | |
4. | ALA4373347 | ADME | Inhibition of CYP450 (unknown origin) | Homo sapiens | 16 | ALA4371085 | protein format | Scientific Literature |