# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4377489 | Binding | Inhibition of recombinant full-length human CDK4/cyclinD3 at 1 uM using Rb fragment as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 41 | ALA4376814 | protein complex format | Scientific Literature | |
2. | ALA4377491 | Binding | Inhibition of recombinant full-length human CDK6/cyclinD3 at 1 uM using histone H1 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 41 | ALA4376814 | protein complex format | Scientific Literature | |
3. | ALA4377493 | Binding | Inhibition of recombinant full-length human CDK9/cyclinT1 at 1 uM using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC peptide as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 41 | ALA4376814 | protein complex format | Scientific Literature | |
4. | ALA4377495 | Binding | Inhibition of recombinant full-length human CDK4/cyclinD3 at 500 nM using Rb fragment as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 31 | ALA4376814 | protein complex format | Scientific Literature | |
5. | ALA4377496 | Binding | Inhibition of recombinant full-length human CDK6/cyclinD3 at 500 nM using histone H1 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 30 | ALA4376814 | protein complex format | Scientific Literature | |
6. | ALA4377497 | Binding | Inhibition of recombinant full-length human CDK9/cyclinT1 at 500 nM using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC peptide as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 38 | ALA4376814 | protein complex format | Scientific Literature | |
7. | ALA4377498 | Functional | Antiproliferative activity against human A549 cells assessed as inhibition of cell viability at 1 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | ALA4376814 | cell-based format | Scientific Literature | |
8. | ALA4377499 | Functional | Antiproliferative activity against human A549 cells assessed as inhibition of cell viability at 10 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | ALA4376814 | cell-based format | Scientific Literature | |
9. | ALA4377500 | Functional | Antiproliferative activity against human H1299 cells assessed as inhibition of cell viability at 1 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | ALA4376814 | cell-based format | Scientific Literature | |
10. | ALA4377501 | Functional | Antiproliferative activity against human H1299 cells assessed as inhibition of cell viability at 10 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | ALA4376814 | cell-based format | Scientific Literature |