# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321597 | Binding | Inhibition of HK2 (unknown origin) using glucose-6-phosphate dehydrogenase as substrate preincubated for 10 mins followed by substrate addition | Homo sapiens | 4 | ALA4316646 | single protein format | Scientific Literature | |
2. | ALA4321598 | Binding | Competitive-inhibition of HK2 (unknown origin) assessed as Km at 10 uM using varying levels of glucose-6-phosphate dehydrogenase as substrate by Lineweaver-burk plot analysis | Homo sapiens | 3 | ALA4316646 | single protein format | Scientific Literature | |
3. | ALA4321599 | ADME | Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 6 | ALA4316646 | cell-based format | Scientific Literature | |
4. | ALA4321600 | Functional | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 6 | ALA4316646 | cell-based format | Scientific Literature | |
5. | ALA4321601 | Functional | Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 6 | ALA4316646 | cell-based format | Scientific Literature | |
6. | ALA4321602 | Functional | Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 6 | ALA4316646 | cell-based format | Scientific Literature |