# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4315486 | Functional | Antiproliferative activity against human MCF7 cells assessed as cell viability at 5 uM incubated for 48 hrs by MTT assay (Rvb = 100 %) | Homo sapiens | 8 | ALA4312005 | cell-based format | Scientific Literature | |
2. | ALA4315487 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 17 | ALA4312005 | cell-based format | Scientific Literature | |
3. | ALA4315488 | Functional | Antiproliferative activity against human A2780 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 17 | ALA4312005 | cell-based format | Scientific Literature | |
4. | ALA4315489 | Functional | Antiproliferative activity against human HT-29 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 17 | ALA4312005 | cell-based format | Scientific Literature | |
5. | ALA4315490 | ADME | Cytotoxicity against human MRC5 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 17 | ALA4312005 | cell-based format | Scientific Literature | |
6. | ALA4315491 | Toxicity | Selectivity index, ratio of IC50 for cytotoxicity against human MRC5 cells to IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 12 | ALA4312005 | cell-based format | Scientific Literature | |
7. | ALA4315492 | Toxicity | Selectivity index, ratio of IC50 for cytotoxicity against human MRC5 cells to IC50 for antiproliferative activity against human A2780 cells | Homo sapiens | 12 | ALA4312005 | cell-based format | Scientific Literature | |
8. | ALA4315493 | Toxicity | Selectivity index, ratio of IC50 for cytotoxicity against human MRC5 cells to IC50 for antiproliferative activity against human HT-29 cells | Homo sapiens | 8 | ALA4312005 | cell-based format | Scientific Literature | |
9. | ALA4315494 | Binding | Inhibition of human COX1 using arachidonic acid as substrate incubated for 2 mins by ELISA method | Homo sapiens | 18 | ALA4312005 | single protein format | Scientific Literature | |
10. | ALA4315495 | Binding | Inhibition of human COX2 using arachidonic acid as substrate incubated for 2 mins by ELISA method | Homo sapiens | 18 | ALA4312005 | single protein format | Scientific Literature | |
11. | ALA4315496 | Binding | Selectivity index, ratio of IC50 for inhibition of human COX1 to IC50 for inhibition of human COX2 | Homo sapiens | 18 | ALA4312005 | assay format | Scientific Literature | |
12. | ALA4315497 | Functional | Antiinflammatory activity against albino rats assessed as inhibition of carrageenan-induced paw edema at 0.5 mmol, po measured after 2 hrs relative to control | Rattus norvegicus | 5 | ALA4312005 | organism-based format | Scientific Literature | |
13. | ALA4315500 | Functional | Antiinflammatory activity against albino rats assessed as inhibition of carrageenan-induced paw edema at 0.5 mmol, po measured after 4 hrs relative to control | Rattus norvegicus | 5 | ALA4312005 | organism-based format | Scientific Literature | |
14. | ALA4315523 | Functional | Cell cycle arrest in human MCF7 cells assessed as subG1 accumulation at 1 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 0.6 to 3 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
15. | ALA4315524 | Functional | Cell cycle arrest in human MCF7 cells assessed as subG1 accumulation at 5 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 0.6 to 3 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
16. | ALA4315525 | Functional | Cell cycle arrest in human MCF7 cells assessed as subG1 accumulation at 10 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 0.6 to 3 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
17. | ALA4315526 | Functional | Cell cycle arrest in human MCF7 cells assessed as G1 accumulation at 1 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 49.6 to 55.1 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
18. | ALA4315527 | Functional | Cell cycle arrest in human MCF7 cells assessed as G1 accumulation at 5 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 49.6 to 55.1 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
19. | ALA4315528 | Functional | Cell cycle arrest in human MCF7 cells assessed as G1 accumulation at 10 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 49.6 to 55.1 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature | |
20. | ALA4315529 | Functional | Cell cycle arrest in human MCF7 cells assessed as S phase accumulation at 1 uM incubated for 24 hrs by propidium iodide based flow cytometry (Rvb = 17.3 to 28.5 %) | Homo sapiens | 4 | ALA4312005 | cell-based format | Scientific Literature |