Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 80 mg/kg, ip measured after 4 to 24 hrs by Bioluminescence imaging analysis
Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 40 mg/kg, ip measured after 24 to 48 hrs by Bioluminescence imaging analysis
Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 40 mg/kg, ip measured after 4 hrs by Bioluminescence imaging analysis
Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 10 mg/kg, ip administered 24 hrs prior to 40 mg/kg, ip dosing for 4 hrs followed by CA4P dosing at 30 mg/kg, ip and measured after 4 to 24 hrs by bioluminescence imaging analysis
Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 10 mg/kg, ip administered 6 hrs prior to 40 mg/kg, ip dosing and measured after 24 hrs by bioluminescence imaging analysis
Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 10 mg/kg, ip administered 6 hrs prior to 40 mg/kg, ip dosing and measured after 4 hrs by bioluminescence imaging analysis relative to control
Induction of vascular damage in human PC3 cells harboring DAB2IP-luc xenografted in Copenhagen rat assessed as reduction in light emission at 10 mg/kg, ip measured after 4 to 24 hrs by Bioluminescence imaging analysis
Inhibition of bovine brain tubulin polymerization preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry-based spectrophotometric method
Inhibition of [3H]colchicine binding to tubulin (unknown origin) at 5 uM measured after 10 mins by beckman scintillation counting method relative to control