# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4384938 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
2. | ALA4384939 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
3. | ALA4384942 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 10 to 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA4384943 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 10 to 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
5. | ALA4384944 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in LPS-induced creatine kinase levels at 10 to 20 uM preincubated for 1 hr followed by LPS stimulation for 5 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4384956 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in LPS-induced LDH release at 10 to 20 uM preincubated for 1 hr followed by LPS stimulation for 5 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
7. | ALA4384958 | B | Inhibition of TLR4 in Sprague Dawley rat cardiomyocytes assessed as reduction in LPS induced LDH levels by measuring NADH levels at 10 to 20 uM preincubated for 1 hr followed by induction of hypoxia measured after 5 hrs by colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
8. | ALA4384959 | F | Antiinflammatory activity in human macrophages assessed reduction in LPS-induced TLR4 expression at 10 uM pretreated for 30 mins followed by LPS stimulation for 4 hrs by FACS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA4384960 | F | Antiinflammatory activity in human macrophages assessed reduction in TLR4 expression at 10 uM after 4 hrs by FACS analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |