# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4339960 | B | Displacement of [3H]-mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates incubated for 60 mins by Cheng and Prusoff equation analysis by scintillation counting analysis | Cavia porcellus | 17 | tissue-based format | Scientific Literature | ||
2. | ALA4339961 | B | Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cerebral cortex homogenates incubated for 60 mins by Cheng and Prusoff equation analysis by scintillation counting analysis | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
3. | ALA4339962 | B | Selectivity index, ratio of Ki for displacement of [3H]-mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates to Ki for displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in rat cerebral cortex homogenates | 7 | tissue-based format | Scientific Literature | |||
4. | ALA4339963 | T | Acute toxicity in KM mouse assessed as effect on survival at 50 to 1000 mg/kg, po after 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA4339968 | F | Anti-nociceptive activity in Sprague-Dawley rat assessed as reduction in total time spent licking injected paw during early phase (0 to 5 mins) at 1 to 10 mg/kg, po dosed 1 hr before formalin injection | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4339969 | F | Anti-nociceptive activity in Sprague-Dawley rat assessed as reduction in total time spent licking injected paw during delayed phase (15 to 45 mins) at 1 to 10 mg/kg, po dosed 1 hr before formalin injection | Rattus norvegicus | 1 | organism-based format | Scientific Literature |