# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4480542 | ADME | Cytotoxicity against MDCK cells assessed as reduction in cell viability after 24 hrs by MTT assay | Canis lupus familiaris | 35 | ALA4480367 | cell-based format | Scientific Literature | |
2. | ALA4480543 | Toxicity | Selectivity index, ratio of CC50 for MDCK cells to EC50 for amantadine-sensitive Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) | 35 | ALA4480367 | assay format | Scientific Literature | ||
3. | ALA4480544 | Functional | Antiviral activity against amantadine-resistant Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) infected in MDCK cells after 40 mins by crystal violet staining-based plaque reduction assay | Influenza A virus | 35 | ALA4480367 | organism-based format | Scientific Literature | |
4. | ALA4480545 | Functional | Antiviral activity against amantadine-sensitive Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) infected in MDCK cells after 40 mins by crystal violet staining-based plaque reduction assay | Influenza A virus | 35 | ALA4480367 | organism-based format | Scientific Literature | |
5. | ALA4480546 | Binding | Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 expressed in yeast cells after 46 to 48 hrs | Influenza A virus | 35 | ALA4480367 | cell-based format | Scientific Literature | |
6. | ALA4480547 | Binding | Inhibition of Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 V27A/S31N double mutant expressed in yeast cells after 46 to 48 hrs | Influenza A virus | 35 | ALA4480367 | cell-based format | Scientific Literature | |
7. | ALA4480548 | ADME | Toxicity against yeast assessed as reduction in cell viability | Saccharomyces cerevisiae | 35 | ALA4480367 | organism-based format | Scientific Literature |