| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4414134 | Binding | Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assay | Homo sapiens | 52 | ALA4411335 | assay format | Scientific Literature | |
| 2. | ALA4414135 | Binding | Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluorescence polarization binding assay | Homo sapiens | 52 | ALA4411335 | single protein format | Scientific Literature | |
| 3. | ALA4414136 | Binding | Induction of human c-ABL phosphorylation at Y245/Y412 residues in bacmam-induced HEK-MSR2 cell lysates by in-cell Western blot analysis | Homo sapiens | 52 | ALA4411335 | subcellular format | Scientific Literature | |
| 4. | ALA4414137 | Physicochemical | Kinetic solubility of the compound at pH 7.4 after 1 hr by CLND-based assay | 51 | ALA4411335 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4414138 | ADME | Permeability of the compound at 10 mM after 3 hrs by artificial membrane permeability assay | 51 | ALA4411335 | assay format | Scientific Literature |
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