# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4373124 | Functional | Antiplasmodial activity against chloroquine-sensitive asexual blood stage of Plasmodium falciparum NF54 infected in human RBC assessed as reduction in [3H]hypoxanthine incorporation preincubated for 48 hrs followed by [3H]hypoxanthine addition measured after 24 hrs by liquid scintillation counting method | Plasmodium falciparum | 63 | ALA4371072 | organism-based format | Scientific Literature | |
2. | ALA4373125 | Functional | Antiplasmodial activity against chloroquine-resistant asexual blood stage of Plasmodium falciparum K1 infected in human RBC assessed as reduction in [3H]hypoxanthine incorporation preincubated for 48 hrs followed by [3H]hypoxanthine addition measured after 24 hrs by liquid scintillation counting method | Plasmodium falciparum | 19 | ALA4371072 | organism-based format | Scientific Literature | |
3. | ALA4373126 | Functional | Resistance index, ratio of IC50 for chloroquine-resistant asexual blood stage of Plasmodium falciparum K1 infected in human RBC to IC50 for chloroquine-sensitive asexual blood stage of Plasmodium falciparum NF54 infected in human RBC | 16 | ALA4371072 | assay format | Scientific Literature | ||
4. | ALA4373127 | Binding | Inhibition of beta hematin formation after 5 hrs by NP40 detergent-based assay | 10 | ALA4371072 | assay format | Scientific Literature |