# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4391017 | Functional | Antileishmanial activity against Leishmania mexicana MNYC-BZ/62/M379 promastigotes assessed as metabolic inhibition at 10 ug/ml after 24 hrs by MTT assay relative to control | Leishmania mexicana | 20 | ALA4390645 | organism-based format | Scientific Literature | |
2. | ALA4391018 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/MX/1994/INC5 epimastigotes assessed as metabolic inhibition at 10 ug/ml after 24 hrs by MTT assay relative to control | Trypanosoma cruzi | 21 | ALA4390645 | organism-based format | Scientific Literature | |
3. | ALA4391019 | Functional | Antileishmanial activity against Leishmania mexicana MNYC-BZ/62/M379 promastigotes assessed as growth inhibition measured after 24 hrs by MTT assay | Leishmania mexicana | 8 | ALA4390645 | organism-based format | Scientific Literature | |
4. | ALA4391020 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/MX/1994/INC5 epimastigotes assessed as growth inhibition measured after 24 hrs by MTT assay | Trypanosoma cruzi | 8 | ALA4390645 | organism-based format | Scientific Literature | |
5. | ALA4391021 | ADME | Cytotoxicity against mouse J774.A1 cells assessed as reduction in cell viability measured after 20 hrs by MTT assay | Mus musculus | 8 | ALA4390645 | cell-based format | Scientific Literature | |
6. | ALA4391022 | Toxicity | Selectivity index, ratio of CC50 for mouse J774.A1 cells to IC50 for antileishmanial activity against Leishmania mexicana MNYC-BZ/62/M379 promastigotes | 8 | ALA4390645 | assay format | Scientific Literature | ||
7. | ALA4391023 | Toxicity | Selectivity index, ratio of CC50 for mouse J774.A1 cells to IC50 for antitrypanosomal activity against Trypanosoma cruzi MHOM/MX/1994/INC5 epimastigotes | 8 | ALA4390645 | assay format | Scientific Literature |