# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4347025 | Functional | Antiinflammatory activity in human dendritic cells assessed as CD14-TLR-4 co-localization at 100 uM incubated for 30 mins by DAPI staining based confocal microscopy | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature | |
2. | ALA4347037 | Functional | Antiinflammatory activity in human dendritic cells assessed as reduction in LPS-induced TNFalpha production at 100 uM cotreated with LPS measured after 24 hrs by ELISA | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature | |
3. | ALA4347038 | Functional | Antiinflammatory activity in human dendritic cells assessed as reduction in LPS-induced TNFalpha production at 100 uM pretreated with LPS for 30 mins followed by compound addition measured after 24 hrs by ELISA | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature | |
4. | ALA4347041 | Functional | Antiinflammatory activity in human dendritic cells assessed as reduction in LPS-induced CD83 expression on cell surface at 100 uM pretreated with LPS upto 6 hrs followed by compound addition measured after 24 hrs by FACS analysis | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature | |
5. | ALA4347042 | Functional | Antiinflammatory activity in human dendritic cells assessed as reduction in LPS-induced CD86 expression on cell surface at 100 uM pretreated with LPS upto 6 hrs followed by compound addition measured after 24 hrs by FACS analysis | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature | |
6. | ALA4347043 | Functional | Antiinflammatory activity in human dendritic cells assessed as reduction in LPS-induced TNFalpha production at 100 uM pretreated with LPS up to 6 hrs followed by compound addition measured after 24 hrs by ELISA | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature | |
7. | ALA4347045 | Functional | Antiinflammatory activity in human dendritic cells assessed as reduction in CD14 receptor cell surface expression at 100 uM incubated for 30 mins by flow cytometric analysis | Homo sapiens | 1 | ALA4346658 | cell-based format | Scientific Literature |