| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4410884 | Binding | Binding affinity to wild-type human partial length SLK (S14 to A307 residues) expressed in bacterial expression system assessed as residual binding level at 10 uM by Kinomescan method | Homo sapiens | 1 | ALA4406912 | assay format | Scientific Literature | |
| 2. | ALA4410885 | Binding | Inhibition of human N-terminal GST-tagged EGFR (696 to 1022 residues) expressed in Sf21 insect cells by HTRF assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 3. | ALA4410886 | Binding | Inhibition of human N-terminal GST-tagged EGFR L858R mutant (696 to 1022 residues) expressed in Sf21 insect cells by HTRF assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 4. | ALA4410887 | Binding | Inhibition of human N-terminal GST-tagged EGFR double T790M/L858R mutant (696 to 1022 residues) expressed in Sf21 insect cells by HTRF assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 5. | ALA4410888 | Binding | Inhibition of human N-terminal GST-tagged EGFR triple T790M/L858R/C797S mutant (696 to 1022 residues) expressed in Sf21 insect cells by HTRF assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 6. | ALA4410889 | Binding | Inhibition of EGFR (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in cell growth incubated for 72 hrs in presence of 1 ug/ml Cetuximab by celltiter-glo luminescent cell viability assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 7. | ALA4410890 | Binding | Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in cell growth incubated for 72 hrs in presence of 1 ug/ml Cetuximab by celltiter-glo luminescent cell viability assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 8. | ALA4410891 | Binding | Inhibition of EGFR double T790M/L858R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in cell growth incubated for 72 hrs in presence of 1 ug/ml Cetuximab by celltiter-glo luminescent cell viability assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 9. | ALA4410892 | Binding | Inhibition of EGFR triple T790M/L858R/C797S mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in cell growth incubated for 72 hrs in presence of 1 ug/ml Cetuximab by celltiter-glo luminescent cell viability assay | Homo sapiens | 5 | ALA4406912 | cell-based format | Scientific Literature | |
| 10. | ALA4410893 | Binding | Allosteric inhibition of human N-terminal GST-tagged EGFR double T790M/L858R mutant (696 to 1022 residues) expressed in Sf21 insect cells assessed as change in inhibition rate in presence of 1 to 1000 uM ATP by HTRF assay | Homo sapiens | 2 | ALA4406912 | cell-based format | Scientific Literature | |
| 11. | ALA4410894 | Binding | Inhibition of recombinant human His-tagged KIT V559D/V654A double mutant expressed in baculovirus expression system at 10 uM by kinomescan assay | Homo sapiens | 1 | ALA4406912 | assay format | Scientific Literature | |
| 12. | ALA4410895 | Binding | Inhibition of tracer 236 binding to recombinant full length human GST-tagged SLK expressed in baculovirus expression system measured after 60 mins by Lanthascreen assay relative to control | Homo sapiens | 1 | ALA4406912 | assay format | Scientific Literature | |
| 13. | ALA5143769 | Binding | Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) | Homo sapiens | 36 | ALA5143505 | single protein format | Scientific Literature |
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