# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4336751 | Binding | Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assay | Homo sapiens | 11 | ALA4334469 | single protein format | Scientific Literature | |
2. | ALA4336752 | Binding | Inhibition of recombinant human POP assessed as affinity constant of first step of the binding event pre-incubated for 2 hrs before addition of ZGP-pNA substrate and measured every 30 secs for first 60 mins followed by every 2 mins for next 5 hrs by dilution assay | Homo sapiens | 3 | ALA4334469 | single protein format | Scientific Literature | |
3. | ALA4336753 | Binding | Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA substrate and measured every 30 secs for first 60 mins followed by every 2 mins for next 5 hrs by dilution assay | Homo sapiens | 4 | ALA4334469 | single protein format | Scientific Literature | |
4. | ALA4336754 | Binding | Inhibition of recombinant human POP assessed as association rate constant pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assay | Homo sapiens | 3 | ALA4334469 | single protein format | Scientific Literature | |
5. | ALA4336755 | Binding | Inhibition of recombinant human POP assessed as dissociation rate constant pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assay | Homo sapiens | 3 | ALA4334469 | single protein format | Scientific Literature | |
6. | ALA4336756 | Binding | Inhibition of recombinant human POP assessed as residence time pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assay | Homo sapiens | 5 | ALA4334469 | single protein format | Scientific Literature | |
7. | ALA4336757 | Binding | Inhibition of human recombinant FAP at 100 uM using fluorogenic DPP substrate1 relative to control | Homo sapiens | 10 | ALA4334469 | single protein format | Scientific Literature | |
8. | ALA4336759 | Binding | Inhibition of recombinant human POP pre-incubated for 2 hrs before addition of ZGP-pNA substrate by absorbance assay | Homo sapiens | 1 | ALA4334469 | single protein format | Scientific Literature | |
9. | ALA4336760 | Unassigned | Drug metabolism in buffer assessed as formation of [(2R)-1-(2-benzyl-3-oxo-isoindoline-4-carbonyl)pyrrolidin-2-yl]boronic acid after 10 mins by LC-MS analysis | 1 | ALA4334469 | assay format | Scientific Literature |