# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4421913 | B | Inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as residual enzyme activity for geranylgeranylation of K-Ras4B at 50 uM incubated for 30 mins in presence of [3H]GGPP by scintillation counting assay relative to control | Rattus norvegicus | 701 | assay format | Patent Bioactivity Data | ||
2. | ALA4421914 | B | Inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as residual enzyme activity for geranylgeranylation of RhoA at 50 uM incubated for 30 mins in presence of [3H]GGPP by scintillation counting assay relative to control | Rattus norvegicus | 128 | assay format | Patent Bioactivity Data | ||
3. | ALA4421916 | B | Inhibition of rat recombinant geranylgeranyltransferase type I expressed in Escherichia coli assessed as reduction in geranylgeranylation of RhoA incubated for 30 mins in presence of [3H]GGPP by scintillation counting assay relative to control | Rattus norvegicus | 87 | assay format | Patent Bioactivity Data | ||
4. | ALA4421918 | B | Inhibition of RabGGTase (unknown origin) using YPTI as substrate protein and [3H]geranylgeranyl pyrophosphate incubated for 20 mins by scintillation counting assay | Homo sapiens | 9 | protein complex format | Patent Bioactivity Data | ||
5. | ALA4421919 | B | Inhibition of rat recombinant FTase alpha/beta expressed in Escherichia coli using K-Ras4B as a substrate as and [3H]farnesyl pyrophosphate incubated for 30 mins by scintillation counting assay | Rattus norvegicus | 9 | assay format | Patent Bioactivity Data |