# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4341304 | Binding | Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 27 | ALA4340526 | cell-based format | Scientific Literature | |
2. | ALA4341305 | Binding | Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility at 100 uM measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis relative to control | Homo sapiens | 2 | ALA4340526 | cell-based format | Scientific Literature | |
3. | ALA4341332 | Binding | Poison activity at TOP1 in human MCF7 cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 27 | ALA4340526 | cell-based format | Scientific Literature |