#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4414331	B	Activation of human Gal4-fused RXRalpha LBD transfected in HEK293T after 14 to 16 hrs by dual-glo luciferase reporter gene assay	Homo sapiens	23	ALA4411340	assay format	Scientific Literature
2.	ALA4414332	B	Activation of human Gal4-fused RXRbeta LBD transfected in HEK293T after 14 to 16 hrs by dual-glo luciferase reporter gene assay	Homo sapiens	23	ALA4411340	assay format	Scientific Literature
3.	ALA4414333	B	Activation of human Gal4-fused RXRgamma LBD transfected in HEK293T after 14 to 16 hrs by dual-glo luciferase reporter gene assay	Homo sapiens	22	ALA4411340	assay format	Scientific Literature
4.	ALA4414334	B	Activation of human Gal4-fused RXRalpha LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to bexarotene	Homo sapiens	26	ALA4411340	assay format	Scientific Literature
5.	ALA4414335	B	Activation of human Gal4-fused RXRbeta LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to bexarotene	Homo sapiens	26	ALA4411340	assay format	Scientific Literature
6.	ALA4414336	B	Activation of human Gal4-fused RXRgamma LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to bexarotene	Homo sapiens	25	ALA4411340	assay format	Scientific Literature
7.	ALA4414337	B	Activation of human Gal4-fused PPARalpha LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to GW7647	Homo sapiens	25	ALA4411340	assay format	Scientific Literature
8.	ALA4414339	B	Activation of human Gal4-fused PPARgamma LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to rosiglitazone	Homo sapiens	25	ALA4411340	assay format	Scientific Literature
9.	ALA4414341	B	Activation of human Gal4-fused PPARdelta LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to L165,041	Homo sapiens	17	ALA4411340	assay format	Scientific Literature
10.	ALA4414344	A	Cytotoxicity against human HepG2 cells up to 50 uM after 48 hrs by WST1 assay	Homo sapiens	27	ALA4411340	cell-based format	Scientific Literature
11.	ALA4414345	P	Aqueous solubility of the compound in distilled water after 24 hrs by HPLC analysis		4	ALA4411340	small-molecule physicochemical format	Scientific Literature
12.	ALA4414347	A	Metabolic stability in Sprague-Dawley rat liver microsomes assessed as remaining parent compound level at 10 uM preincubated for 5 mins with NADPH generating system followed by liver microsomes addition and measured after 60 mins by HPLC analysis	Rattus norvegicus	4	ALA4411340	microsome format	Scientific Literature
13.	ALA4414348	B	Binding affinity to recombinant RXRalpha (unknown origin) by isothermal titration calorimetry	Homo sapiens	6	ALA4411340	single protein format	Scientific Literature
14.	ALA4414349	B	Binding affinity to recombinant PPARgamma (unknown origin) by isothermal titration calorimetry	Homo sapiens	6	ALA4411340	single protein format	Scientific Literature
15.	ALA4414355	B	Activation of RXR in human HepG2 cells assessed as increase in ApoE mRNA expression at 1 uM after 12 hrs followed by renewal of medium containing test compounds after 6 hrs by PCR analysis	Homo sapiens	1	ALA4411340	cell-based format	Scientific Literature
16.	ALA4414356	A	Activation of LXR in human HepG2 cells assessed as increase in SREBP-1c mRNA expression at 1 uM after 12 hrs followed by renewal of medium containing test compounds after 6 hrs by PCR analysis	Homo sapiens	2	ALA4411340	cell-based format	Scientific Literature
17.	ALA4414358	B	Activity at LXR in human HepG2 cells assessed as reduction in T0901317-induced activation of SREBP-1c mRNA expression at 1 uM after 12 hrs followed by renewal of medium containing test compounds after 6 hrs by PCR analysis	Homo sapiens	1	ALA4411340	cell-based format	Scientific Literature
18.	ALA4414359	B	Antagonist activity at human Gal4-fused LXRalpha expressed in HEK293T cells assessed as inhibition of T0901317 induced response at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay	Homo sapiens	1	ALA4411340	cell-based format	Scientific Literature
19.	ALA4414360	A	Drug uptake in C57BL6/JRj mouse plasma at 10 mg/kg, po administered as single dose and measured after 2 hrs by LS-MS analysis	Mus musculus	1	ALA4411340	organism-based format	Scientific Literature
20.	ALA4414361	A	Drug uptake in C57BL6/JRj mouse liver at 10 mg/kg, po administered as single dose and measured after 2 hrs by LS-MS analysis	Mus musculus	1	ALA4411340	organism-based format	Scientific Literature