| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4413391 | A | Antagonist activity at serotonin receptor in human PBMC assessed as inhibition of PMA-stimulated superoxide anion generation at 10 uM preincubated for 1 hr followed by PMA-stimulation and measured after 30 mins by spectrophotometric method | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 2. | ALA4413392 | A | Cytotoxicity against human Jurkat cells assessed as reduction in cell viability at 1 uM after 24 hrs by trypan blue exclusion assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4413393 | B | Inhibition of DGKalpha in OKT3-induced human Jurkat cells harboring SAP ShRNA assessed as restoration of restimulation-induced cell death at 1 uM measured after 24 hrs by trypan blue exclusion method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4413394 | B | Inhibition of DGKalpha in PHA-induced human Jurkat cells harboring SAP ShRNA assessed as restoration of restimulation-induced cell death at 1 uM measured after 24 hrs by trypan blue exclusion method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4413395 | B | Effect on TCR signaling in OKT3-induced human T-cells harboring SiRNA assessed as restoration of restimulation-induced cell death at 1 to 10 uM preincubated for 30 mins followed by OKT3 stimulation and measured 24 hrs post dose by propidium iodide staining based flow cytometry | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA4413398 | B | Inhibition of DGKalpha in OKT3-induced human T cells harboring SAP SiRNA assessed as restoration of restimulation-induced cell death at >=5 uM preincubated for 30 mins followed by OKT3 stimulation and measured 24 hrs post dose by propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4413402 | B | Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mins by ADP-Glo luminescence assay | Sus scrofa | 3 | cell-based format | Scientific Literature |
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