# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4478464 | B | Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue preincubated for 30 mins followed by substrate addition for 1 hr by HTRF assay | Homo sapiens | 26 | ALA4477213 | single protein format | Scientific Literature | |
2. | ALA4478465 | B | Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue preincubated for 30 mins followed by substrate addition for 1 hr by HTRF assay | Homo sapiens | 26 | ALA4477213 | single protein format | Scientific Literature | |
3. | ALA4478466 | B | Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 mins by flow cytometry | Homo sapiens | 26 | ALA4477213 | cell-based format | Scientific Literature | |
4. | ALA4478473 | P | Aqueous solubility of the compound in PBS at pH 7.4 after 1 hr by LC/MS analysis | 11 | ALA4477213 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4478474 | P | Aqueous solubility of the compound in FaSIF at pH 7.4 after 1 hr by LC/MS analysis | 12 | ALA4477213 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4478480 | B | Ratio of IC50 for pan Pim in human KMS-12-BM cells to IC50 for full length recombinant Pim-2 (unknown origin) | Homo sapiens | 4 | ALA4477213 | cell-based format | Scientific Literature |