# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4397085 | A | Activation of non-specific gene expression in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as CMV driven gene expression incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay | Homo sapiens | 102 | cell-based format | Scientific Literature | ||
2. | ALA4397086 | B | Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as LTR-driven gene expression incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter cellular assay | Human immunodeficiency virus 1 | 102 | cell-based format | Scientific Literature | ||
3. | ALA4397089 | P | Aqueous solubility of the compound in 0.01M HCl at pH 2 by nephelometry | 13 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4397090 | P | Aqueous solubility of the compound in phosphate buffer at pH 6.5 by nephelometry | 13 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4397091 | A | Half-life in human liver microsomes at 1 uM in presence of NADPH regenerating system by LC/MS analysis | Homo sapiens | 13 | microsome format | Scientific Literature | ||
6. | ALA4397092 | A | Intrinsic clearance in human liver microsomes assessed per mg protein at 1 uM in presence of NADPH regenerating system by LC/MS analysis | Homo sapiens | 13 | microsome format | Scientific Literature | ||
7. | ALA4397093 | A | Half-life in mouse liver microsomes at 1 uM in presence of NADPH regenerating system by LC/MS analysis | Mus musculus | 13 | microsome format | Scientific Literature | ||
8. | ALA4397094 | A | Intrinsic clearance in mouse liver microsomes assessed per mg protein at 1 uM in presence of NADPH regenerating system by LC/MS analysis | Mus musculus | 13 | microsome format | Scientific Literature |