| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4316276 | B | Inhibition of tubulin polymerization (unknown origin) incubated for 15 mins followed by GTP addition and measured for 20 mins by spectrophotometry | Homo sapiens | 70 | ALA4312029 | protein complex format | Scientific Literature | |
| 2. | ALA4316277 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 96 hrs by MTT assay | Homo sapiens | 70 | ALA4312029 | cell-based format | Scientific Literature | |
| 3. | ALA4316278 | B | Inhibition of [3H]colchicine binding to tubulin (unknown origin) at 5 uM incubated for 10 mins by DEAE-cellulose filter method relative to control | Homo sapiens | 68 | ALA4312029 | protein complex format | Scientific Literature | |
| 4. | ALA4316279 | F | Cytotoxicity against human KU812 cells expressing IM- sensitive wild type Bcr/Abl assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA4312029 | cell-based format | Scientific Literature | |
| 5. | ALA4316280 | F | Cytotoxicity against human LAMA84-s cells expressing IM-sensitive wild type Bcr/Abl assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA4312029 | cell-based format | Scientific Literature | |
| 6. | ALA4316281 | F | Cytotoxicity against IM resistant human LAMA84-r cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA4312029 | cell-based format | Scientific Literature | |
| 7. | ALA4316282 | F | Cytotoxicity against human KBM5 cells expressing IM- sensitive wild type Bcr/Abl assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA4312029 | cell-based format | Scientific Literature | |
| 8. | ALA4316283 | F | Cytotoxicity against human KBM5 cells expressing IM-resistant Bcr/Abl T315I mutant assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA4312029 | cell-based format | Scientific Literature | |
| 9. | ALA4316284 | F | Cytotoxicity against human U343MG cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 10. | ALA4316285 | F | Cytotoxicity against human U87MG cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 11. | ALA4316286 | F | Cytotoxicity against human T98G cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 12. | ALA4316287 | F | Cytotoxicity against human SK-N-BE cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 13. | ALA4316288 | F | Cytotoxicity against human SK-N-BE(2)C cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 14. | ALA4316289 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 15. | ALA4316290 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 16. | ALA4316291 | F | Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 17. | ALA4316292 | F | Cytotoxicity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 18. | ALA4316293 | F | Cytotoxicity against human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA4312029 | cell-based format | Scientific Literature | |
| 19. | ALA4316294 | F | Antitumor activity against human T24 cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor volume at 20 mg/kg, ip administered every 2 days for 40 days and measured on day 40 | Homo sapiens | 1 | ALA4312029 | organism-based format | Scientific Literature | |
| 20. | ALA4316295 | F | Antitumor activity against human T24 cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor weight at 20 mg/kg, ip administered every 2 days for 40 days and measured on day 40 | Homo sapiens | 1 | ALA4312029 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!