| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4427852 | Binding | Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-COOH as substrate in presence of ATP by IMAP fluorescence polarization assay | Homo sapiens | 37 | ALA4425185 | cell-based format | Scientific Literature | |
| 2. | ALA4427853 | Binding | Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for 1 hr followed by stimulation with LPS for 4 to 5 hrs measured after 30 mins by spectrophotometric analysis | Homo sapiens | 10 | ALA4425185 | cell-based format | Scientific Literature | |
| 3. | ALA4427863 | Binding | Ratio of IC50 for IRAK4 inhibition in human THP1-XBlue cells to IC50 for inhibition of human IRAK4 | Homo sapiens | 10 | ALA4425185 | cell-based format | Scientific Literature |
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