# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4337922 | F | Antibacterial activity against Clostridium difficile 4118 ATCC BAA 1870 assessed as bacterial growth inhibition incubated for 48 hrs under anaerobic condition by CLSI protocol-based assay | Clostridioides difficile | 60 | ALA4334504 | organism-based format | Scientific Literature | |
2. | ALA4337923 | F | Antibacterial activity against Clostridium difficile VPI 10463 ATCC 43255 assessed as bacterial growth inhibition incubated for 48 hrs under anaerobic condition by CLSI protocol based assay | Clostridioides difficile | 60 | ALA4334504 | organism-based format | Scientific Literature | |
3. | ALA4337925 | A | Cytotoxicity against human Caco2 cells at > 256 uM measured after 2 hrs by MTS assay | Homo sapiens | 8 | ALA4334504 | cell-based format | Scientific Literature | |
4. | ALA4337926 | A | Cytotoxicity against human HRT18 cells at > 256 uM measured after 2 hrs by MTS assay | Homo sapiens | 8 | ALA4334504 | cell-based format | Scientific Literature | |
5. | ALA4337927 | A | Cytotoxicity against African green monkey Vero cells at > 256 uM measured after 2 hrs by MTS assay | Chlorocebus sabaeus | 8 | ALA4334504 | cell-based format | Scientific Literature | |
6. | ALA4337928 | A | Effect on growth of Lactobacillus gasseri EX336960VC03 HM 400 measured after 48 hrs in anaerobic conditions by CLSI method | Lactobacillus gasseri EX336960VC03 | 16 | ALA4334504 | assay format | Scientific Literature | |
7. | ALA4337929 | A | Effect on growth of Lactobacillus casei ATCC 334 measured after 48 hrs in anaerobic conditions by CLSI method | Lacticaseibacillus paracasei | 16 | ALA4334504 | assay format | Scientific Literature | |
8. | ALA4337930 | A | Effect on growth of Lactobacillus crispatus JV-V01 HM 103 measured after 48 hrs in anaerobic conditions by CLSI method | Lactobacillus crispatus JV-V01 | 16 | ALA4334504 | assay format | Scientific Literature | |
9. | ALA4337931 | A | Effect on growth of Bifidobacterium bifidum 212A ATCC 11863 measured after 48 hrs in anerobic conditions by CLSI method | Bifidobacterium bifidum | 16 | ALA4334504 | organism-based format | Scientific Literature | |
10. | ALA4337932 | A | Effect on growth of Escherichia coli ATCC 25922 assessed as bacterial growth inhibition measured after 16 to 18 hrs by CLSI method | Escherichia coli | 16 | ALA4334504 | organism-based format | Scientific Literature | |
11. | ALA4337933 | A | Effect on growth of Enterobacter cloacae ATCC BAA 1143 assessed as bacterial growth inhibition measured after 16 to 18 hrs grown in tryptic soy medium by CLSI method | Enterobacter cloacae | 16 | ALA4334504 | organism-based format | Scientific Literature | |
12. | ALA4337934 | P | Aqueous solubility of compound in PBS buffer at 1 to 100 ug/ml at pH 7.3 to 7.5 measured after 24 hrs by HPLC analysis | 5 | ALA4334504 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4337935 | A | Stability of compound in simulated gastric fluid assessed as parent compound remaining at pH 1.6 measured after 4 hrs by HPLC analysis | 5 | ALA4334504 | assay format | Scientific Literature | ||
14. | ALA4337936 | A | Stability of compound in simulated gastric fluid assessed as parent compound remaining at pH 1.6 measured after 8 hrs by HPLC analysis | 5 | ALA4334504 | assay format | Scientific Literature | ||
15. | ALA4337937 | A | Stability of compound in simulated intestinal fluid assessed as parent compound remaining at pH 6 measured after 4 hrs by HPLC analysis | 5 | ALA4334504 | assay format | Scientific Literature | ||
16. | ALA4337938 | A | Stability of compound in simulated intestinal fluid assessed as parent compound remaining at pH 6 measured after 8 hrs by HPLC analysis | 5 | ALA4334504 | assay format | Scientific Literature |