| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4324041 | Binding | Inhibition of human topoisomerase 2alpha mediated decatenation at 30 uM using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP addition and measured after 1 hr by ethidium bromide staining based gel electrophoresis method relative to control | Homo sapiens | 30 | ALA4321838 | single protein format | Scientific Literature | |
| 2. | ALA4324042 | Binding | Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP addition and measured after 1 hr by ethidium bromide staining based gel electrophoresis method | Homo sapiens | 30 | ALA4321838 | single protein format | Scientific Literature | |
| 3. | ALA4324060 | ADME | Drug metabolism in CD-1 mouse active microsomes assessed as CYP450-mediated oxidative phase 1 metabolite formation measured within 30 mins by LC-MS/MS analysis | Mus musculus | 8 | ALA4321838 | microsome format | Scientific Literature | |
| 4. | ALA4324061 | ADME | Metabolic stability in CD-1 mouse inactive microsomes incubated for 1 hr by LC-MS/MS analysis | Mus musculus | 11 | ALA4321838 | microsome format | Scientific Literature | |
| 5. | ALA4324063 | ADME | Drug metabolism in CD-1 mouse active microsomes assessed as metabolite formation at rate of first-order kinetics by LC-MS/MS analysis | Mus musculus | 7 | ALA4321838 | microsome format | Scientific Literature |
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