# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4427467 | B | Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assay | Homo sapiens | 13 | ALA4425169 | single protein format | Scientific Literature | |
2. | ALA4427468 | B | Displacement of [35S]MK-499 from human ERG | Homo sapiens | 13 | ALA4425169 | single protein format | Scientific Literature | |
3. | ALA4427469 | B | Selectivity ratio of IC50 for human ERG to IC50 for ROMK (unknown origin) | Homo sapiens | 10 | ALA4425169 | assay format | Scientific Literature | |
4. | ALA4427470 | B | Inhibition of ROMK (unknown origin) expressed in CHO cells after 6 mins by electrophysiological assay | Homo sapiens | 5 | ALA4425169 | cell-based format | Scientific Literature | |
5. | ALA4427471 | B | Inhibition of human ERG after 6 mins by electrophysiological assay | Homo sapiens | 5 | ALA4425169 | single protein format | Scientific Literature | |
6. | ALA4427472 | B | Selectivity ratio of IC50 for human ERG to IC50 for ROMK (unknown origin) expressed in CHO cells by electrophysiological assay | Homo sapiens | 5 | ALA4425169 | cell-based format | Scientific Literature | |
7. | ALA4427474 | F | Diuretic activity in Sprague-Dawley rat at 3 mg/kg via oral gavage administered 30 mins prior to void induction by loading saline measured upto 4 hrs relative to vehicle treated control | Rattus norvegicus | 5 | ALA4425169 | organism-based format | Scientific Literature | |
8. | ALA4427475 | F | Diuretic activity in Sprague-Dawley rat at 10 mg/kg via oral gavage administered 30 mins prior to void induction by loading saline measured upto 4 hrs relative to vehicle treated control | Rattus norvegicus | 3 | ALA4425169 | organism-based format | Scientific Literature | |
9. | ALA4427476 | F | Natriuretic activity in Sprague-Dawley rat at 3 mg/kg via oral gavage administered 30 mins prior to void induction by loading saline measured upto 4 hrs relative to vehicle treated control | Rattus norvegicus | 5 | ALA4425169 | organism-based format | Scientific Literature | |
10. | ALA4427477 | F | Natriuretic activity in Sprague-Dawley rat at 10 mg/kg via oral gavage administered 30 mins prior to void induction by loading saline measured upto 4 hrs relative to vehicle treated control | Rattus norvegicus | 3 | ALA4425169 | organism-based format | Scientific Literature |