# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307631 | Binding | Inhibition of N-terminal GST-tagged human IRAK4 (2 to end residues) expressed in baculovirus infected Sf9 cells using Ser/Thr 7 peptide as substrate in presence of ATP after 1 hr by Z'-LYTE assay | Homo sapiens | 6 | ALA4304808 | cell-based format | Scientific Literature | |
2. | ALA4307632 | Binding | Protac activity at E3 ubiquitin ligase/IRAK4 in human MCF7 cells assessed as IRAK4 degradation after 24 hrs by Western blot analysis | Homo sapiens | 6 | ALA4304808 | cell-based format | Scientific Literature | |
3. | ALA4307633 | Binding | Protac activity at E3 ubiquitin ligase/IRAK4 in human MCF7 cells assessed as IRAK4 degradation after 24 hrs by Western blot analysis relative to control | Homo sapiens | 6 | ALA4304808 | cell-based format | Scientific Literature |